ZUG, Switzerland--(BUSINESS WIRE)--Galderma:

Galderma delivered strong performance

• Galderma delivered at the top end of its 2022 revenue guidance with 13.9% year-on-year net sales growth on a constant currency basis at 3,760 M USD and delivered above its 2022 profitability guidance with 14.5% Core EBITDA year-on-year growth on a constant currency basis at 791 M USD
  • Sustained growth momentum fueled by continued strong performance in Injectable Aesthetics and Dermatological Skincare with year-on-year net sales growth of 22.3% and 30.7% respectively, on a constant currency basis, primarily driven by volume growth
  • Topline growth and margin expansion demonstrate continued strong operating and commercial performance despite a challenging external environment

Significant progress in advancing the R&D pipeline with notable milestones for differentiated biologic entries expected to fuel significant long-term sustainable growth

• Galderma completed three phase III clinical trials studying nemolizumab, a first-in-class investigational monoclonal antibody directed against the IL-31 receptor alpha with a central role in pruritus (itch) and skin inflammation, in the treatment of prurigo nodularis and atopic dermatitis
• Galderma presented positive data from two phase III studies on RelabotulinumtoxinA (QM-1114), a novel liquid formulation botulinumtoxinA for the treatment of glabellar lines (frown) and lateral canthal lines (crow’s feet). As already announced, both studies met their primary endpoints and the results showed both rapid onset of action and long duration of action through to six months

Net sales growth and significant Core EBITDA margin expansion expected in 2023

• In 2023, Galderma expects to deliver 6-9% net sales growth on a constant currency basis, and 200-300 bps Core EBITDA margin expansion (vs 2022). The 2023 Core EBITDA margin expansion guidance includes significant nemolizumab costs